Nervous systems are composed of various cell types, but the extent of cell type diversity is poorly understood. We constructed a cellular taxonomy of one cortical region, primary visual cortex, in adult mice on the basis of single-cell RNA sequencing. We identified 49 transcriptomic cell types, incl . The maturational rate of mice does not linearly correlate with humans—it occurs times faster during the first month of life and 45 times faster over the next five months, during which mice pass through their mature adult stage. Mature adult mice range in age from 3 - 6 months; the life phase equivalent for humans ranges from 20 - 30 years.
A mousing exercise to help beginning computer users learn how to use a mouse. Mousercise! Practice your mousing skills with the following Mousercise. Click . Neural stem cells (NSCs) generate neurons throughout life in the mammalian hippocampus. However, the potential for long-term self-renewal of individual NSCs within the adult brain remains unclear.
For the mature adult group, mice should be at least three months old because, although they are sexually mature by 35 days, relatively rapid maturational growth continues for most biological. Zapala, M. A. et al. Adult mouse brain gene expression patterns bear an embryologic imprint. Proc. Natl Acad. Sci. USA , – ().