MPS II is a mucopolysaccharide disease known as Hunter syndrome. It takes its name from Charles Hunter, the professor of medicine in Manitoba, Canada, who first described two brothers with the disease in MPS II has a wide range of symptoms that vary in severity and can be managed and treated with enzyme replacement therapies. Hunter syndrome symptoms vary in severity and include: Stiff joints Thickening of facial features including nostrils, lips and tongue Delayed appearance of teeth or wide spaces between teeth Larger than normal head, wide chest and short neck Hearing loss that gets worse with time Delayed growth.
Physical manifestations for some people with Hunter syndrome include distinct facial features, a large head, and an enlarged abdomen. People with Hunter syndrome may also experience hearing loss, thickening of the heart valves leading to a decline in cardiac function, obstructive airway disease, sleep apnea, and enlargement of the liver and spleen. Range of . Hunter syndrome is a resource for people with Hunter syndrome (MPS II), their family and friends, and healthcare providers. Learn more.